Corium is committed to developing novel therapies that have the potential to treat neuroscience disorders.
Attention-deficit/hyperactivity disorder (ADHD) is a mental health disorder that can cause a pattern of inattentiveness and/or above-normal levels of hyperactive and impulsive behaviors. People with ADHD may have difficulty paying attention and controlling impulsive behaviors. They may also be restless and may be overly active. ADHD is not just a childhood disorder. Although the symptoms of ADHD begin in childhood, ADHD can continue through adolescence and adulthood.
Alzheimer's disease is a progressive and irreversible brain disorder. It involves changes in brain tissue including abnormal buildup of proteins as well as loss of neuron function.1 The resulting damage leads to the loss of remembering, reasoning, and thinking abilities. The related behavioral changes include the loss of independence in activities of daily living and self-care.2,3 Dementia ranges in severity from mild, when it is just beginning to affect a person's functioning, to moderate, and severe, when the person must depend on others for the basic activities of day-to-day life. Patients with advanced Alzheimer's disease may be unable to chew and swallow easily.4
An estimated 6.2 million Americans were living with Alzheimer's disease in 2021, with a possible rise to 13.8 million by 2060.5 Globally, more than 55 million people have dementia, and Alzheimer's disease may account for 60 to 70 percent of patients, according to the World Health Organization.6
The US Centers for Disease Control and Prevention estimates that in 2020, more than 11 million Americans provided an estimated 15.3 billion hours of unpaid care for patients with Alzheimer’s disease.2
References: 1. National Institute on Aging. Alzheimer’s Disease Fact Sheet. July 8, 2021. Accessed at https://www.nia.nih.gov/health/alzheimers-disease-fact-sheet. 2. Centers for Disease Control and Prevention. Alzheimer’s Disease. June 22, 2021. Accessed at https://www.cdc.gov/dotw/alzheimers/index.html. 3. Matthews KA, Xu W, Gaglioti AH, et al. Racial and ethnic estimates of Alzheimer's disease and related dementias in the United States (2015-2060) in adults aged ≥65 years. Alzheimer’s Dement. 2019;15(1):17-24. doi:10.1016/j.jalz.2018.06.3063 4. National Institute on Aging. Caring for a person with late-stage Alzheimer's disease. May 27, 2021. Accessed at https://www.nia.nih.gov/health/caring-late-stage-alzheimers-disease. 5. 2021 Alzheimer's disease facts and figures. Alzheimer’s Dement. 2021;17(3)327-406. doi: 10.1002/alz.12328. Epub 2021 Mar 23. PMID: 33756057. 6. World Health Organization. Dementia. September 2, 2021. Accessed at https://www.who.int/news-room/fact-sheets/detail/dementia.